Cellular Contractile Forces Influence Chromatin Density
Category: Research Poster
Author(s): Skylar Stephan
Presenter(s): Skylar Stephan
Mentors(s): Ashok Prasad, Rosaline Danzman
The cytoskeleton exerts forces on the nuclei and can affect its shape. This effect was shown to also affect the condensed chromatin depending on how the forces were changed. Using MATLAB's Sobel edge detection the amount of edges and the area can be quantified. These two measures can then be used to find the condensed chromatin density for the nuclei. Having this code run through all the images in the four different treatment groups reveals the significant differences between each group.