Wireless Electrochemical Immunosensing: Portable Quantitation Via NFC Potentiostats
Category: Community Engagement Poster
Author(s): Wyatt Hummel
Presenter(s): Wyatt Hummel
ABSTRACT: Infectious diseases such as COVID-19 continue to pose significant global health challenges, particularly in resource-limited settings where access to laboratory diagnostics is constrained. In addition to diagnostic testing, rapid and accurate quantification of immune system biomarkers is essential for monitoring disease progression, evaluating vaccine efficacy, and guiding public health interventions. To address this need, we present a novel magnetic bead-based electrochemical immunoassay compatible with a portable, near-field communication (NFC)-enabled potentiostat, enabling wireless detection of antibody neutralizing efficiency. Our platform translates biochemical recognition events into quantitative electrochemical signals using enzyme-mediated redox reactions, achieving high sensitivity and specificity comparable to standard ELISA techniques. The device demonstrates strong potential for decentralized, point-of-care testing by leveraging smartphone compatibility and low-cost assay design, this system offers a scalable solution for infectious disease monitoring.